Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 8/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129860 | 0.86 | TSHR (0.65) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9301802 | 0.85 | TBXA2R (0.48) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL8840163 | 0.84 | TBXA2R (0.79) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9130507 | 0.83 | SGMS1 (0.68) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9303040 | 0.81 | TBXA2R (0.45) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9127591 | 0.81 | SGMS1 (0.76) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9128585 | 0.80 | SGMS1 (0.62) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL11342587 | 0.80 | PPARA (0.66) | SGMS1TBXA2RMEN1KMT2AALDH1A1 | |
| SCHEMBL6695825 | 0.79 | PTGS2 (0.56) | MEN1KMT2AALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL8840166 | 0.78 | TBXA2R (0.64) | SGMS1TBXA2RTBXAS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360909-A | THROMBOXANE A2 ANTAGONIST | TERUMO KABUSHIKI KAISHA (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0562796-A1 | Phenoxyacetic acid compounds and medical preparations containing them | TERUMO KABUSHIKI KAISHA (JP) | 1993-09-29 | — | — | EP | disclosed |