Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 10/20 | 0.64 |
| ▸ | F2 | P00734 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850482 | 0.89 | SGMS1 (0.66) | SGMS1F2PLGTBXA2R | |
| SCHEMBL9127591 | 0.87 | SGMS1 (0.76) | SGMS1TBXA2RHTT | |
| SCHEMBL9850678 | 0.86 | F2 (0.64) | SGMS1F2PLGTBXA2R | |
| SCHEMBL9127503 | 0.86 | TBXA2R (0.69) | SGMS1F2PLGTBXA2R | |
| SCHEMBL9850586 | 0.86 | SGMS1 (0.56) | SGMS1F2PLGTBXA2RHSD17B10 | |
| SCHEMBL9127768 | 0.85 | TBXA2R (0.57) | SGMS1F2PLGTBXA2R | |
| SCHEMBL9850521 | 0.85 | SGMS1 (0.60) | SGMS1F2PLGTBXA2R | |
| SCHEMBL9127508 | 0.85 | F2 (0.68) | SGMS1F2PLGTBXA2R | |
| SCHEMBL10446945 | 0.85 | F2 (0.66) | SGMS1F2PLGTBXA2R | |
| SCHEMBL9850395 | 0.85 | SGMS1 (0.55) | SGMS1F2PLGTBXA2RHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | claimed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | claimed |
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |