SCHEMBL9850482

SCHEMBL9850482

O=C(O)CNC(=O)COc1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SGMS1 Q86VZ5 9/20 0.66
TBXA2R P21731 5/20 0.62
F2 P00734 2/20 0.58
PLG P00747 1/20 0.58
TBXAS1 P24557 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9617068 0.92 SGMS1 (0.63) SGMS1TBXA2RTBXAS1
SCHEMBL9127503 0.92 TBXA2R (0.69) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9130577 0.89 SGMS1 (0.64) SGMS1TBXA2RF2PLG
SCHEMBL9836463 0.89 TBXA2R (0.65) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9813021 0.85 ALDH1A1 (0.62) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9850678 0.85 F2 (0.64) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9129284 0.85 TBXA2R (0.66) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9850521 0.84 SGMS1 (0.60) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9127508 0.84 F2 (0.68) SGMS1TBXA2RF2PLGTBXAS1
SCHEMBL9850603 0.83 SGMS1 (0.59) SGMS1TBXA2RF2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435085-A1 Phenoxyalkylcarboxylic amides, process for their preparation and drug containing them Roche Diagnostics GmbH (DE) 1991-07-03 EP disclosed