Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178998 | 0.55 | — | — | |
| SCHEMBL5914302 | 0.54 | BTK (0.64) | BTK | |
| SCHEMBL6906047 | 0.53 | — | — | |
| SCHEMBL21456835 | 0.52 | BTK (0.55) | BTK | |
| SCHEMBL13217143 | 0.52 | — | — | |
| SCHEMBL19347197 | 0.51 | — | — | |
| SCHEMBL166882 | 0.51 | — | — | |
| SCHEMBL1928370 | 0.51 | — | — | |
| SCHEMBL20686936 | 0.49 | — | — | |
| SCHEMBL4621674 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438063-A | Hypotensive agents, cardiac insufficiency, increased intraocular pressure, and CNS disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-08-01 | — | — | US | claimed |