Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130667 | 1.00 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9131409 | 0.94 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9131404 | 0.94 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9132395 | 0.92 | ALDH1A1 (0.44) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9132386 | 0.92 | ALDH1A1 (0.44) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9131388 | 0.91 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1PLK1KMT2AMEN1 | |
| SCHEMBL9131400 | 0.91 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1PLK1KMT2AMEN1 | |
| SCHEMBL9135856 | 0.89 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9135850 | 0.89 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PLK1TDP1KMT2A | |
| SCHEMBL9135710 | 0.87 | PLK1 (0.58) | PLK1TDP1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |