Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SHBG | P04278 | 2/20 | 0.45 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702311 | 0.86 | CYP19A1 (0.67) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL6832273 | 0.85 | CYP19A1 (0.65) | CYP19A1ALDH1A1SHBGSERPINA6 | |
| SCHEMBL3658069 | 0.85 | CYP19A1 (0.65) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL8209838 | 0.83 | CYP19A1 (0.62) | CYP19A1 | |
| SCHEMBL3660113 | 0.79 | CYP19A1 (0.58) | CYP19A1 | |
| SCHEMBL17831183 | 0.79 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL12413521 | 0.79 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL21807725 | 0.79 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL20088312 | 0.79 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL868884 | 0.79 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528876-B1 | 2-IODO-3-KETO-DELTA 4 -STEROIDS, PROCESS FOR PRODUCING THEM AND THEIR FURTHER PROCESSING | SCHERING AG (DE) | 1995-04-12 | — | — | EP | claimed |
| US-5391778-A | 2-iodo-3-keto-Δ4 steroids, process for their production, as well as their further processing | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-02-21 | — | — | US | claimed |
| EP-0528876-B1 | 2-IODO-3-KETO-DELTA 4 -STEROIDS, PROCESS FOR PRODUCING THEM AND THEIR FURTHER PROCESSING | SCHERING AG (DE) | 1995-04-12 | — | — | EP | disclosed |
| US-5391778-A | 2-iodo-3-keto-Δ4 steroids, process for their production, as well as their further processing | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-02-21 | — | — | US | disclosed |
| EP-0528876-A1 | 2-IODO-3-KETO-DELTA?4 -STEROIDS, PROCESS FOR PRODUCING THEM AND THEIR FURTHER PROCESSING. | SCHERING AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991017175-A1 | 2-IODO-3-KETO-DELTA4-STEROIDS, PROCESS FOR PRODUCING THEM AND THEIR FURTHER PROCESSING | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-11-14 | — | — | WO | disclosed |