SCHEMBL9130703

SCHEMBL9130703

O=C(NCc1cccnc1)NCc1cccnc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FES P07332 1/20 0.81
RET P07949 1/20 0.81
MARK3 P27448 1/20 0.81
TYK2 P29597 1/20 0.81
FLT4 P35916 1/20 0.81
SYK P43405 1/20 0.81
CLK2 P49760 1/20 0.81
CLK4 Q9HAZ1 1/20 0.81
RECQL P46063 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
NAMPT P43490 1/20 0.68
P2RX7 Q99572 1/20 0.68
ALDH1A1 P00352 1/20 0.68
KMT2A Q03164 4/20 0.68
MEN1 O00255 2/20 0.68
MAPT P10636 1/20 0.68
POLB P06746 1/20 0.66
NPSR1 Q6W5P4 1/20 0.64
CYP1A2 P05177 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460250 1.00 FES (0.81) FESRETMARK3TYK2FLT4
SCHEMBL29684017 0.95 NAMPT (0.76) FESRETMARK3TYK2FLT4
SCHEMBL14323610 0.92 FLT4 (0.97) FESRETMARK3TYK2FLT4
SCHEMBL18327711 0.92 FES (0.91) FESRETMARK3TYK2FLT4
SCHEMBL18317546 0.90 FLT4 (1.00) FESRETMARK3TYK2FLT4
SCHEMBL18317181 0.90 FLT4 (1.00) FESRETMARK3TYK2FLT4
SCHEMBL18317211 0.90 FLT4 (1.00) FESRETMARK3TYK2FLT4
SCHEMBL18317214 0.90 FLT4 (1.00) FESRETMARK3TYK2FLT4
SCHEMBL18317996 0.90 FLT4 (1.00) FESRETMARK3TYK2FLT4
SCHEMBL1514550 0.90 FLT4 (1.00) FESRETMARK3TYK2FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230313401-A1 COPPER ELECTROPLATING BATH Atotech Deutschland GmbH & Co. KG (DE) 2023-10-05 US disclosed
US-20230313401-A1 COPPER ELECTROPLATING BATH Atotech Deutschland GmbH & Co. KG (DE) 2023-10-05 US disclosed
US-20230220558-A1 AN AQUEOUS BASIC ETCHING COMPOSITION FOR THE TREATMENT OF SURFACES OF METAL SUBSTRATES Atotech Deutschland GmbH & Co. KG (DE) 2023-07-13 US disclosed
US-20230220558-A1 AN AQUEOUS BASIC ETCHING COMPOSITION FOR THE TREATMENT OF SURFACES OF METAL SUBSTRATES Atotech Deutschland GmbH & Co. KG (DE) 2023-07-13 US disclosed
US-10882842-B2 Pyridinium compounds, a synthesis method therefor, metal or metal alloy plating baths containing said pyridinium compounds and a method for use of said metal or metal alloy plating baths ATOTECH DEUTSCHLAND GMBH (DE) 2021-01-05 US disclosed
US-20200231565-A1 PYRIDINIUM COMPOUNDS, A SYNTHESIS METHOD THEREFOR, METAL OR METAL ALLOY PLATING BATHS CONTAINING SAID PYRIDINIUM COMPOUNDS AND A METHOD FOR USE OF SAID METAL OR METAL ALLOY PLATING BATHS ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) 2020-07-23 US disclosed
EP-3360988-B1 PYRIDINIUM COMPOUNDS, A SYNTHESIS METHOD THEREFOR, METAL OR METAL ALLOY PLATING BATHS CONTAINING SAID PYRIDINIUM COMPOUNDS AND A METHOD FOR USE OF SAID METAL OR METAL ALLOY PLATING BATHS ATOTECH DEUTSCHLAND GMBH (DE) 2019-06-26 EP disclosed
US-5386008-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1995-01-31 US disclosed
US-5244998-A Flexible coatings THE DOW CHEMICAL COMPANY (US) 1993-09-14 US disclosed
US-5147905-A Cationic polyepoxide and epoxy resins for electrodeposition; flexibility; workability THE DOW CHEMICAL COMPANY (US) 1992-09-15 US disclosed
WO-1991018034-A1 ADVANCED AND UNADVANCED COMPOSITIONS, NUCLEOPHILIC DERIVATIVES THEREOF AND CURABLE AND COATING COMPOSITIONS THEREOF THE DOW CHEMICAL COMPANY (US) 1991-11-28 WO disclosed
US-5021471-A Polyepoxides and epoxy resins modified by a pyridine compound and acid; solvent- and water-systems; coatings, molding materials and castings; chemical resistance; flexibility THE DOW CHEMICAL COMPANY (US) 1991-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231565-A1 PYRIDINIUM COMPOUNDS, A SYNTHESIS METHOD THEREFOR, METAL OR METAL ALLOY PLATING BATHS CONTAINING SAID PYRIDINIUM COMPOUNDS AND A METHOD FOR USE OF SAID METAL OR METAL ALLOY PLATING BATHS ADAR, MAP2K7, MAP2K5 FES 2157/4885RET 4057/4885MARK3 1593/4885
US-10882842-B2 Pyridinium compounds, a synthesis method therefor, metal or metal alloy plating baths containing said pyridinium compounds and a method for use of said metal or metal alloy plating baths ADAR, MAP2K7, MAP2K5 FES 2157/4885RET 4057/4885MARK3 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.