Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162987 | 0.89 | TP53 (0.64) | PLA2G4BPLA2G4AL3MBTL1ALDH1A1TP53 | |
| SCHEMBL9130182 | 0.86 | GAA (0.62) | PLA2G4BALDH1A1TP53 | |
| SCHEMBL1023839 | 0.85 | TP53 (0.70) | PLA2G4BPLA2G4AL3MBTL1TP53TSHR | |
| SCHEMBL21384542 | 0.84 | CYP1A2 (0.68) | PLA2G4BPLA2G4AL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5206359 | 0.84 | TP53 (0.73) | PLA2G4BPLA2G4ATP53TSHR | |
| SCHEMBL9161795 | 0.84 | TP53 (0.73) | PLA2G4BPLA2G4ATP53TSHR | |
| SCHEMBL8728342 | 0.84 | TP53 (0.73) | PLA2G4BPLA2G4ATP53TSHR | |
| SCHEMBL1022325 | 0.84 | TP53 (0.73) | PLA2G4BPLA2G4ATP53TSHR | |
| SCHEMBL4209056 | 0.84 | TP53 (0.73) | PLA2G4BPLA2G4ATP53TSHR | |
| SCHEMBL10045771 | 0.84 | TP53 (0.73) | PLA2G4BPLA2G4ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |