Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595033 | 0.89 | NPC1 (0.49) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL9131206 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL18608342 | 0.86 | GBA1 (0.48) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL9128642 | 0.84 | HPGD (0.44) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL18608559 | 0.83 | NPC1 (0.53) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL18608415 | 0.83 | MAPT (0.56) | SMN1; SMN2RAB9ANPC1HTTGAA | |
| SCHEMBL18608548 | 0.83 | NPC1 (0.48) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL18608343 | 0.82 | NR3C1 (0.50) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL18608346 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL9128607 | 0.82 | KDM4E (0.51) | SMN1; SMN2RAB9ANPC1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387588-A | Antiulcer agents | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-02-07 | — | — | US | disclosed |
| US-5252572-A | Antiulcer agent | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-10-12 | — | — | US | disclosed |
| US-5158951-A | Pyridopyrimidine derivatives useful in treatment of ulcers | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYAR RT. (HU) | 1992-10-27 | — | — | US | disclosed |