Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 10/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971747 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1CYP3A4MAPK1 | |
| SCHEMBL4116469 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 | |
| SCHEMBL29184903 | 0.77 | ESR1 (0.46) | TSHR | |
| SCHEMBL9158083 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 | |
| SCHEMBL9133521 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 | |
| SCHEMBL4050620 | 0.75 | CNR2 (0.47) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 | |
| SCHEMBL7201693 | 0.75 | TSHR (0.45) | ALDH1A1TSHRL3MBTL1MAPK1TDP1 | |
| SCHEMBL11433950 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 | |
| SCHEMBL9131897 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 | |
| SCHEMBL131813 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TSHRCNR2L3MBTL1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476645-B1 | Calcium uptake inhibitors | MERRELL DOW PHARMA (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5409942-A | Administering 1-phenyl-3-aryl-2-propyne-1-ones compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0250193-B1 | Photoreactive lenses | MARCONI GEC LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-5223518-A | Controlling intake in leukocytes and platelets | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0476645-A1 | Calcium uptake inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4818096-A | SUNGLASSES; BENZO OR NAPHTHOPYRANS WITH NITROGEN CONTAINING SUBSTITUENTS | THE PLESSEY COMPANY PLC (GB) | 1989-04-04 | — | — | US | disclosed |
| EP-0250193-A2 | Photoreactive lenses | GEC-MARCONI LIMITED (GB) | 1987-12-23 | — | — | EP | disclosed |