SCHEMBL913221

SCHEMBL913221

N#CCC(Cl)(Cl)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1982189 0.69
SCHEMBL12123460 0.69 ALDH1A1 (0.35)
SCHEMBL7883058 0.69 ALDH1A1 (0.35)
SCHEMBL5087892 0.69 ALDH1A1 (0.35)
Water SCHEMBL8986201 0.69 LOX (0.30)
SCHEMBL181823 0.67
SCHEMBL11045713 0.67
Methyl Alcohol SCHEMBL7435412 0.67
Methane SCHEMBL10705120 0.66 MEN1 (0.31)
SCHEMBL1164528 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858907-B2 Kinase modulators RHIZEN PHARMACEUTICALS AG (CH) 2024-01-02 US disclosed
EP-3098230-B1 THIOETHER COMPOUND FOR THE PROTECTION OF THE 2'-HYDROXY GROUP IN NUCLEOSIDES TO BE USED IN OLIGONUCLEOTIDE SYNTHESIS. BONAC CORP (JP) 2020-05-06 EP disclosed
CN-107102082-B Method for determining residual quantity of amitraz and metabolite thereof in royal jelly by liquid chromatography-mass spectrometry/mass spectrometry 浙江省检验检疫科学技术研究院 2019-12-17 CN disclosed
US-10442783-B2 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases RHIZEN PHARMACEUTICALS SA (CH) 2019-10-15 US disclosed
US-9988415-B2 Glycoside compound, method for producing thioether, ether, method for producing ether, method for producing glycoside compound, method for producing nucleic acid BONAC CORPORATION (JP) 2018-06-05 US disclosed
EP-2749565-B1 NUCLEOSIDE PHOSPHORAMIDATES FOR PRODUCING NUCLEIC ACIDS BONAC CORP (JP) 2017-05-31 EP disclosed
EP-3098230-A1 THIOETHER COMPOUND FOR THE PROTECTION OF THE 2'-HYDROXY GROUP IN NUCLEOSIDES TO BE USED IN OLIGONUCLEOTIDE SYNTHESIS. Bonac Corporation (JP) 2016-11-30 EP disclosed
US-9481702-B2 Glycoside compound, method for producing thioether, ether, method for producing ether, method for producing glycoside compound, method for producing nucleic acid BONAC CORPORATION (JP) 2016-11-01 US disclosed
US-9421209-B2 Kinase modulators RHIZEN PHARMACEUTICALS SA (CH) 2016-08-23 US disclosed
US-20160176810-A1 GLYCOSIDE COMPOUND, METHOD FOR PRODUCING THIOETHER, ETHER, METHOD FOR PRODUCING ETHER, METHOD FOR PRODUCING GLYCOSIDE COMPOUND, METHOD FOR PRODUCING NUCLEIC ACID BONAC CORPORATION (JP) 2016-06-23 US disclosed
WO-1994008984-A1 NOVEL TAXANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1994-04-28 WO disclosed
US-4652563-A PYRIDAZINONES SUBSTITUTED WITH CYCLOPROPYLMETHOXYETHYL GROUP SMITH KLINE & FRENCH LABORATORIES LTD. (GB) 1987-03-24 US disclosed
US-4324905-A PROSTAGLANDIN F2A, DRUGS THE UPJOHN COMPANY (US) 1982-04-13 US disclosed
US-4172206-A CRYSTALLINE PROSTAGLANDINS THE UPJOHN COMPANY (US) 1979-10-23 US disclosed
US-4017535-A OXYTOCICS, ABORTION, HYPOTENSIVE, ANTISECRETORY THE UPJOHN COMPANY (US) 1977-04-12 US disclosed
US-4011249-A Substituted keto and alkoxy carbonyl esters of 16-substituted PGE2 type compounds THE UPJOHN COMPANY (US) 1977-03-08 US disclosed
US-4010172-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1977-03-01 US disclosed
US-3998869-A PROSTAGLANDIN E2; HYPOTENSIVE AGENTS, OXYTOCICS, PROPHYLAXIS, ANTISECRETORY AGENTS THE UPJOHN COMPANY (US) 1976-12-21 US disclosed
US-3994956-A OXYTOCICS, ANTISECRETORY, HYPOTENSIVE, PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-11-30 US disclosed
US-3994957-A OXYTOCICS, ANTISECRETORY, HYPOTENSIVE, INTERMEDIATES, PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-11-30 US disclosed