Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | PTPRB | P23467 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | TLR4 | O00206 | 4/20 | 0.41 |
| ▸ | CD14 | P08571 | 4/20 | 0.41 |
| ▸ | LY96 | Q9Y6Y9 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.41 |
| ▸ | GSTA1 | P08263 | 6/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 6/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133022 | 0.94 | TLR4 (0.43) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL14617494 | 0.83 | PTPRC (0.57) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL9132993 | 0.81 | ELANE (0.33) | ELANECD69 | |
| SCHEMBL14617492 | 0.77 | TLR4 (0.57) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL13987040 | 0.77 | ELANE (0.58) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL14617493 | 0.71 | ELANE (0.53) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL13987036 | 0.71 | GSTA1 (0.52) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL14159148 | 0.71 | PTPRC (0.43) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL30388098 | 0.70 | ELANE (0.51) | PTPRCPTPN2PTPN1PTPRBPTPN11 | |
| SCHEMBL16545623 | 0.69 | CD69 (0.65) | PTPRCPTPN2PTPN1PTPRBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412114-A | Etherification, optical resolution, steric hindrance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| US-5231196-A | Optic separation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-27 | — | — | US | disclosed |