Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | MAOA | P21397 | 9/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134150 | 1.00 | KDM1A (0.52) | KDM1ADEGS1MAOBMAOACYP2C19 | |
| SCHEMBL9135013 | 0.90 | KDM1A (0.60) | KDM1ADEGS1CYP2C9LMNACYP3A4 | |
| SCHEMBL9135017 | 0.90 | KDM1A (0.60) | KDM1ADEGS1CYP2C9LMNACYP3A4 | |
| SCHEMBL28632233 | 0.89 | DEGS1 (0.47) | KDM1ADEGS1MAOBMAOACYP2C19 | |
| SCHEMBL2261976 | 0.84 | MAOB (0.65) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| SCHEMBL10540521 | 0.84 | MAOB (0.65) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| SCHEMBL8845464 | 0.84 | MAOB (0.65) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| SCHEMBL9131537 | 0.83 | HTR2A (0.54) | KDM1ALMNACYP3A4HTR2CHSD17B10 | |
| SCHEMBL9131533 | 0.83 | HTR2A (0.54) | KDM1ALMNACYP3A4HTR2CHSD17B10 | |
| SCHEMBL8024246 | 0.80 | HTR2C (0.56) | KDM1AMAOBMAOACYP2C19CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5444147-A | Hydroxy derivatives form polyethers and polyesters, crosslinking by opening of cyclopropane ring | HAY ALLAN S (CA) | 1995-08-22 | — | — | US | disclosed |