⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758885 | 0.72 | — | — | |
| SCHEMBL25278760 | 0.72 | — | — | |
| SCHEMBL16344793 | 0.71 | CTDSP1 (0.38) | — | |
| SCHEMBL758078 | 0.69 | — | — | |
| SCHEMBL1439486 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL9135177 | 0.68 | NPC1 (0.30) | — | |
| SCHEMBL8559299 | 0.65 | — | — | |
| SCHEMBL1192425 | 0.64 | EPHX1 (0.32) | — | |
| SCHEMBL25311548 | 0.62 | — | — | |
| SCHEMBL18297156 | 0.61 | CTDSP1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446062-A | Antiallergens, antiinflammatory agent | ABBOTT LABORATORIES (US) | 1995-08-29 | — | — | US | disclosed |
| US-5426111-A | Antiallergens, antiinflammatory agent | ABBOTT LABORATORIES (US) | 1995-06-20 | — | — | US | disclosed |
| US-5350765-A | Treatment of allergic and inflammatory diseases | ABBOTT LABORATORIES (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1994004528-A1 | ETHER-CONTAINING INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-03-03 | — | — | WO | disclosed |
| US-5268379-A | Quinolin-1-one structure | ABBOTT LABORATORIES (US) | 1993-12-07 | — | — | US | disclosed |