Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518709 | 0.96 | OPRL1 (0.36) | OPRL1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8518707 | 0.96 | OPRL1 (0.36) | OPRL1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8518711 | 0.96 | OPRL1 (0.36) | OPRL1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9181582 | 0.92 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9181599 | 0.92 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9181594 | 0.92 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14274436 | 0.92 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9136523 | 0.90 | OPRL1 (0.34) | OPRL1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9136412 | 0.88 | ESR2 (0.34) | OPRL1ESR2 | |
| SCHEMBL9136818 | 0.88 | ESR2 (0.34) | OPRL1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |