Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.59 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643693 | 0.85 | MAPT (0.57) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL6169580 | 0.84 | PTGER4 (0.64) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL7105521 | 0.84 | PRKCI (0.71) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL11642598 | 0.84 | MAPT (0.56) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL11642681 | 0.83 | NPC1 (0.73) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL2344997 | 0.83 | GAA (0.63) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL5924534 | 0.83 | MAPT (0.64) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL10600114 | 0.83 | PRKCI (0.54) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL542066 | 0.83 | PRKCI (0.69) | ALDH1A1MAPTGAAMAPK1KDM4E | |
| SCHEMBL11648013 | 0.82 | MAPT (0.53) | ALDH1A1MAPTGAAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453533-A | Enzyme inhibitor | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM (US) | 1995-09-26 | — | — | US | disclosed |