SCHEMBL2344997

SCHEMBL2344997

CC(=O)Nc1ccc(C(=O)O)cc1N

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.63
KDM4E B2RXH2 8/20 0.63
MAPT P10636 6/20 0.63
ALDH1A1 P00352 6/20 0.63
HPGD P15428 4/20 0.63
GFER P55789 4/20 0.63
THRB P10828 3/20 0.63
HTT P42858 1/20 0.63
PLEC Q15149 1/20 0.63
NEU3 Q9UQ49 1/20 0.60
HSD17B10 Q99714 4/20 0.58
NPC1 O15118 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
GLA P06280 1/20 0.58
RCE1 Q9Y256 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PTGER4 P35408 1/20 0.55
PRKCI P41743 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8374327 0.98 GAA (0.61) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL7105521 0.87 PRKCI (0.71) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL10600114 0.86 PRKCI (0.54) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL15942895 0.86 HDAC1 (0.61) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL11789120 0.83 ALDH1A1 (0.58) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL3891611 0.83 NPC1 (0.64) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL9136207 0.83 ALDH1A1 (0.62) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL8367216 0.82 HDAC1 (0.71) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL1067119 0.81 PRKCI (0.73) GAAKDM4EMAPTALDH1A1HPGD
SCHEMBL8887281 0.81 GAA (0.58) GAAKDM4EMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5602277-A Substituted benzene derivatives useful as neuraminidase inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 1997-02-11 US claimed
WO-1996030329-A1 SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS, INCORPORATED (US) 1996-10-03 WO claimed
EP-4343775-A1 A METHOD FOR DETERMINING A MEDICAL OUTCOME FOR AN INDIVIDUAL, RELATED ELECTRONIC SYSTEM AND COMPUTER PROGRAM SurgeCare (FR) 2024-03-27 EP disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
EP-3320921-B1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA INC (US) 2022-01-05 EP disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
WO-1996039838-A1 METHODS OF INHIBITING BACTERIAL SIALIDASE UNIVERSITY OF ALABAMA (US) 1996-12-19 WO disclosed
EP-0685470-A2 Benzene derivatives and pharmaceutical composition Kureha Chemical Industry Co., Ltd. (JP) 1995-12-06 EP disclosed
WO-1995028376-A1 INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE AND METHODS OF MAKING AND USING THE SAME THE UNIVERSITY OF ALABAMA AT BIRMINGHAM (US) 1995-10-26 WO disclosed
US-5453533-A Enzyme inhibitor THE UNIVERSITY OF ALABAMA AT BIRMINGHAM (US) 1995-09-26 US disclosed
EP-0649883-A1 Pigment compositions CIBA-GEIGY AG (CH) 1995-04-26 EP disclosed
US-5256772-A Colorant for gravure offset or inks, coatings, clarity TOYO INK MANUFACTURING CO., LTD. (JP) 1993-10-26 US disclosed
EP-0480705-A1 Monoazo lake pigment, process for producing the same and its use TOYO INK MANUFACTURING CO., LTD. (JP) 1992-04-15 EP disclosed
US-4810302-A STORAGE STABLE MIXTURES TOYO INK MANUFACTURING CO., LTD. (JP) 1989-03-07 US disclosed
US-4039672-A EMESIS SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1977-08-02 US disclosed