Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833681 | 1.00 | NOTUM (0.50) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| Iodide SCHEMBL28237298 | 0.98 | NOTUM (0.49) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| Hydrochloric Acid SCHEMBL29666952 | 0.98 | NOTUM (0.49) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| SCHEMBL28228519 | 0.85 | NOTUM (0.51) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| Iodide SCHEMBL28254992 | 0.84 | NOTUM (0.50) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| SCHEMBL10331081 | 0.82 | NOTUM (0.49) | NOTUMCNR2SLC6A2SLC6A4BIRC2 | |
| SCHEMBL13227696 | 0.81 | HTR2C (0.41) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| SCHEMBL1573643 | 0.81 | NOTUM (0.47) | NOTUMCNR2KDM4ELMNA | |
| SCHEMBL447188 | 0.80 | NOTUM (0.50) | NOTUMCNR2SLC6A2SLC6A4HTR2C | |
| SCHEMBL1450546 | 0.80 | NOTUM (0.50) | NOTUMCNR2SLC6A2SLC6A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552289-B | Near-infrared fluorescent probe substrate of COMT and application thereof | 无锡尔云科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112552289-A | Near-infrared fluorescent probe substrate of COMT and application thereof | 无锡尔云科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-9926282-B2 | Phthalazinones and isoquinolinones as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-27 | — | — | US | disclosed |
| US-20170355696-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2017-12-14 | — | — | US | disclosed |
| US-8329718-B2 | N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100197716-A1 | N-LINKED HETEROCYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY | 2010-08-05 | — | — | US | disclosed |
| US-7728008-B2 | N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-7550499-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| US-5405968-A | Useful as drugs, for producing singlet oxygen, sensitizers in electrophotographic layers and for photopolymerizations and as laser light sensitive dyes in optical recording media | BASF AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| US-4594303-A | Containing charge generating and charge transfer material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| US-4450219-A | CHARGE GENERATING COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197716-A1 | N-LINKED HETEROCYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | P2RY1, P2RY11, P2RY13 | NOTUM 4169/4885CNR2 33/4885SLC6A2 660/4885 |
| US-20170355696-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | EGFR, WEE1, DPYD | NOTUM 69/4885CNR2 3182/4885SLC6A2 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.