Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228519 | 0.98 | NOTUM (0.51) | NOTUMKMT2AMEN1ALDH1A1CNR2 | |
| Perchlorate SCHEMBL30036840 | 0.89 | NOTUM (0.48) | NOTUMKMT2AMEN1ALDH1A1CNR2 | |
| SCHEMBL10331081 | 0.88 | NOTUM (0.49) | NOTUMCNR2SLC6A2SLC6A4BIRC2 | |
| SCHEMBL1573643 | 0.87 | NOTUM (0.47) | NOTUMALDH1A1CNR2CYP1A2CYP2D6 | |
| Iodide SCHEMBL28237298 | 0.86 | NOTUM (0.49) | NOTUMKMT2AMEN1CNR2SLC6A2 | |
| SCHEMBL30928324 | 0.85 | NOTUM (0.46) | NOTUMKMT2AMEN1ALDH1A1CNR2 | |
| SCHEMBL10331082 | 0.85 | NOTUM (0.46) | NOTUMKMT2AMEN1ALDH1A1CNR2 | |
| SCHEMBL9079557 | 0.85 | NOTUM (0.46) | NOTUMKMT2AMEN1ALDH1A1CNR2 | |
| SCHEMBL29402742 | 0.85 | NOTUM (0.46) | NOTUMKMT2AMEN1ALDH1A1CNR2 | |
| SCHEMBL29833681 | 0.84 | NOTUM (0.50) | NOTUMKMT2AMEN1CNR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099948-A1 | Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents | COLABS INT'L CORP. (US) | 2024-03-28 | — | — | US | disclosed |
| US-11839674-B2 | Compositions comprising silicon dioxide-based particles including one or more agents | CoLabs International Corporation (US) | 2023-12-12 | — | — | US | disclosed |
| US-11724134-B2 | Compositions containing a cellulose derived capsule with a sunscreen active agent | CoLabs International Corporation (US) | 2023-08-15 | — | — | US | disclosed |
| US-11707421-B2 | Compositions containing a flexible derived capsule with an active agent | COLABS INT'L CORP. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230113098-A1 | Compositions Containing a Capsule with an Agent | COLABS INT'L CORP. (US) | 2023-04-13 | — | — | US | disclosed |
| CN-114404610-B | Hyaluronic acid-geraniol polymer prodrug multi-biological response drug delivery system HSSG NPs and preparation method and application thereof | 河南大学 | 2023-02-24 | — | — | CN | disclosed |
| US-11491088-B2 | Compositions containing a capsule with a moisturizing agent | CoLabs International Corporation (US) | 2022-11-08 | — | — | US | disclosed |
| CN-108704134-A | A kind of targeting multifunctional nano grain containing IR780, using and preparation method thereof | 重庆医科大学 | 2018-10-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707421-B2 | Compositions containing a flexible derived capsule with an active agent | CUTA, LIPE, LIPA | NOTUM 37/4885KMT2A 3272/4885MEN1 299/4885 |
| US-11724134-B2 | Compositions containing a cellulose derived capsule with a sunscreen active agent | CUTA, ACMSD, TYR | NOTUM 23/4885KMT2A 4008/4885MEN1 139/4885 |
| US-20230113098-A1 | Compositions Containing a Capsule with an Agent | LIPA, CUTA, FABP4 | NOTUM 28/4885KMT2A 3786/4885MEN1 272/4885 |
| US-11491088-B2 | Compositions containing a capsule with a moisturizing agent | CUTA, LIPA, PLIN5 | NOTUM 28/4885KMT2A 3719/4885MEN1 225/4885 |
| US-20240099948-A1 | Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents | MSN, LIPE, CUTA | NOTUM 164/4885KMT2A 2603/4885MEN1 84/4885 |
| US-11839674-B2 | Compositions comprising silicon dioxide-based particles including one or more agents | MSN, LIPE, CUTA | NOTUM 167/4885KMT2A 2641/4885MEN1 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.