Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 1.00 |
| ▸ | IMPDH1 | P20839 | 1/20 | 1.00 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389000 | 1.00 | IMPDH2 (1.00) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| SCHEMBL28194905 | 0.98 | IMPDH2 (0.96) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL27803164 | 0.98 | IMPDH2 (0.96) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| Methyl Alcohol SCHEMBL27844152 | 0.94 | IMPDH2 (0.89) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL7364790 | 0.88 | IMPDH2 (0.77) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| Pyrimidine SCHEMBL28222789 | 0.87 | IMPDH2 (0.75) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| SCHEMBL5015694 | 0.87 | IMPDH2 (0.75) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| Maleic Acid SCHEMBL28775310 | 0.85 | IMPDH2 (0.73) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| Fumaric Acid SCHEMBL28775322 | 0.85 | IMPDH2 (0.73) | IMPDH2IMPDH1GABRPGABRDGABRA1 | |
| SCHEMBL5485659 | 0.85 | IMPDH2 (0.73) | IMPDH2IMPDH1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136744-A | Novel intermediate of 5-cyanoindole and preparation method thereof | 台州职业技术学院 | 2025-06-13 | — | — | CN | claimed |
| CN-120028308-A | Small molecule Raman probe, bar code probe, encoding method and application thereof | 北京大学 | 2025-05-23 | — | — | CN | claimed |
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | claimed |
| CN-118125960-A | Bisindole 3-ketone compound, application and preparation method thereof | 云南农业大学 | 2024-06-04 | — | — | CN | claimed |
| CN-116656352-B | Eutectic solvent and preparation method and application thereof | 河北科技大学 | 2024-05-10 | — | — | CN | claimed |
| CN-110139862-B | Substituted bicyclic heterocyclic derivatives useful as ROMK channel inhibitors | 百时美施贵宝公司 | 2024-01-16 | — | — | CN | claimed |
| CN-116836661-A | Epoxy resin-based conductive adhesive and preparation method thereof | 罗卫中 | 2023-10-03 | — | — | CN | claimed |
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | claimed |
| CN-116656352-A | Eutectic solvent and preparation method and application thereof | 河北科技大学 | 2023-08-29 | — | — | CN | claimed |
| CN-114933550-B | Antibacterial peptide with polyphenyl indolyl amidine, and preparation method and application thereof | 湖南大学 | 2023-07-28 | — | — | CN | claimed |
| CN-1474691-A | Novel uses of combined 5-HT 1A agonists and serotonin reuptake inhibitor | Ĭ��ר���ɷ�����˾ | 2004-02-11 | — | — | CN | claimed |
| US-6509116-B1 | High electromotive force and cyclic property; fast charging and discharging; stable and reactive in acidic ambient; proton charge carrier | NEC TOKIN CORPORATION (JP) | 2003-01-21 | — | — | US | claimed |
| US-20020132164-A1 | Cyclic property and are capable of fast charging and discharging; capacitors | NEC CORPORATION | 2002-09-19 | — | — | US | claimed |
| EP-1147083-A1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-24 | — | — | EP | claimed |
| CN-1072209-C | Benzonitriles and benzofluorides | MERCK PATENT GMBH (DE) | 2001-10-03 | — | — | CN | claimed |
| EP-1071148-A2 | Secondary battery and capacitor using indole polymeric compound | NEC CORPORATION (JP) | 2001-01-24 | — | — | EP | claimed |
| WO-2000040554-A1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-13 | — | — | WO | claimed |
| CN-1047385-C | 3-indolylpiperidine | MERCK PATENT GMBH (DE) | 1999-12-15 | — | — | CN | claimed |
| CN-1137036-A | Benzonitriles and benzofluorides | MERCK PATENT GMBH (DE) | 1996-12-04 | — | — | CN | claimed |
| CN-1114651-A | 3-indolylpiperidine | MERCK PATENT GMBH (DE) | 1996-01-10 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | HIPK1, NEK1, HIPK2 | IMPDH2 846/4885IMPDH1 694/4885GABRP 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.