Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.50 |
| ▸ | PGR | P06401 | 14/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136672 | 1.00 | AR (0.50) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL9139913 | 0.80 | CYP19A1 (0.57) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL9139911 | 0.80 | CYP19A1 (0.57) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL13474804 | 0.77 | AR (0.54) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL13770298 | 0.74 | AR (0.52) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL13770470 | 0.72 | CYP19A1 (0.56) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL5017816 | 0.71 | AR (0.67) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL5017813 | 0.71 | AR (0.67) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL13557243 | 0.71 | CYP19A1 (0.55) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL9138223 | 0.70 | AR (0.53) | ARPGRNR3C2SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478862-A | Having progestational activity with minimum ancillary hormonal activity; antiovulation agents | SRI INTERNATIONAL (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0500899-B1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | STANFORD RES INST INT (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5321044-A | Ovulation suppression | SRI INTERNATIONAL (US) | 1994-06-14 | — | — | US | disclosed |
| US-5116865-A | Antifertility Agents | SRI INTERNATIONAL, A CORP OF CA | 1992-05-26 | — | — | US | disclosed |
| WO-1992004309-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | SRI INTERNATIONAL (US) | 1992-03-19 | — | — | WO | disclosed |