Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.54 |
| ▸ | PGR | P06401 | 14/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770298 | 0.88 | AR (0.52) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL13770350 | 0.82 | CYP19A1 (0.54) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL13770301 | 0.80 | AR (0.50) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL9136672 | 0.77 | AR (0.50) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL9136667 | 0.77 | AR (0.50) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL5017813 | 0.76 | AR (0.67) | ARPGRNR3C2SHBG | |
| SCHEMBL5017816 | 0.76 | AR (0.67) | ARPGRNR3C2SHBG | |
| SCHEMBL13770470 | 0.75 | CYP19A1 (0.56) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL13769109 | 0.74 | AR (0.47) | ARPGRNR3C2SHBG | |
| SCHEMBL9139911 | 0.73 | CYP19A1 (0.57) | ARPGRNR3C2SHBGCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238147-B1 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |