Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425503 | 0.73 | KMT2A (0.45) | NPC1RAB9AKMT2AGLAALDH1A1 | |
| SCHEMBL34651 | 0.71 | — | — | |
| SCHEMBL98748 | 0.71 | — | — | |
| Urea SCHEMBL28133713 | 0.71 | NPC1 (0.49) | NPC1RAB9AKMT2AGLAALDH1A1 | |
| SCHEMBL2004766 | 0.71 | NPC1 (0.52) | NPC1RAB9AKMT2AGLAALDH1A1 | |
| SCHEMBL1324 | 0.71 | NPC1 (0.62) | NPC1RAB9AKMT2AGLAALDH1A1 | |
| SCHEMBL26916822 | 0.70 | NPC1 (0.45) | NPC1RAB9AKMT2AGLANR3C1 | |
| SCHEMBL2418976 | 0.70 | JAK3 (0.44) | NPC1RAB9AKMT2AGLAALDH1A1 | |
| SCHEMBL26917154 | 0.70 | KMT2A (0.42) | NPC1RAB9AKMT2AGLAALDH1A1 | |
| Bromide SCHEMBL6990879 | 0.70 | HRH3 (0.47) | NPC1RAB9AKMT2AGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464759-A | Sequential oligonucleotide syntheses using immunoaffinity techniques | BIONEBRASKA, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5221736-A | Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques | BIONEBRASKA, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0449980-A4 | SEQUENTIAL PEPTIDE AND OLIGONUCLEOTIDE SYNTHESIS USING IMMUNOAFFINITY TECHNIQUES | — | 1991-11-21 | — | — | EP | disclosed |
| EP-0449980-A1 | SEQUENTIAL PEPTIDE AND OLIGONUCLEOTIDE SYNTHESIS USING IMMUNOAFFINITY TECHNIQUES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006936-A1 | SEQUENTIAL PEPTIDE AND OLIGONUCLEOTIDE SYNTHESIS USING IMMUNOAFFINITY TECHNIQUES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1990-06-28 | — | — | WO | disclosed |