Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135644 | 0.95 | AGTR1 (0.61) | AGTR1AGTR2PPARGCYP1A2CYP2C9 | |
| SCHEMBL9137942 | 0.91 | AGTR1 (0.65) | AGTR1AGTR2PPARGKDM4E | |
| SCHEMBL9136736 | 0.85 | AGTR1 (0.65) | AGTR1AGTR2PPARGKDM4E | |
| SCHEMBL9139364 | 0.83 | PPARG (0.66) | AGTR1AGTR2PPARGCYP1A2CYP2C9 | |
| SCHEMBL9137910 | 0.81 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9137178 | 0.79 | PPARG (0.65) | AGTR1AGTR2PPARGCYP1A2CYP2C9 | |
| SCHEMBL9136781 | 0.78 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9087920 | 0.77 | AGTR1 (0.76) | AGTR1AGTR2PPARG | |
| SCHEMBL10443938 | 0.77 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9198204 | 0.76 | AGTR1 (1.00) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |