Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166722 | 0.88 | POLB (0.82) | POLBGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL9136989 | 0.84 | POLB (0.46) | POLBGAAL3MBTL1ALDH1A1TYR | |
| SCHEMBL9713112 | 0.81 | POLB (0.72) | POLBGAAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL11140297 | 0.80 | POLB (0.70) | POLBGAAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2029357 | 0.80 | POLB (0.70) | POLBGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6756690 | 0.80 | POLB (1.00) | POLBGAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL31232896 | 0.80 | POLB (1.00) | POLBGAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL11163516 | 0.79 | POLB (0.68) | POLBGAAL3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL15525257 | 0.77 | POLB (0.66) | POLBGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL9137234 | 0.77 | TYR (0.43) | POLBGAAL3MBTL1ALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475129-A | Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1993025561-A1 | PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-12-23 | — | — | WO | disclosed |