Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166722 | 0.93 | POLB (0.82) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL2029357 | 0.84 | POLB (0.70) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11140297 | 0.84 | POLB (0.70) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL31232896 | 0.84 | POLB (1.00) | POLBGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL6756690 | 0.84 | POLB (1.00) | POLBGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11163516 | 0.83 | POLB (0.68) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL5754367 | 0.81 | CA12 (0.49) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL7088667 | 0.81 | CA12 (0.49) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9136992 | 0.81 | POLB (0.66) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL15525257 | 0.81 | POLB (0.66) | POLBGAAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126371-A | Precancerous skin conditions, acne, psoriasis | BASF AKTEINGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| EP-0176034-A2 | Diaryl acetylenes, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-04-02 | — | — | EP | disclosed |