Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378572 | 0.89 | MEN1 (0.47) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL11127651 | 0.88 | CYP3A4 (0.36) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL8560878 | 0.87 | MEN1 (0.53) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL147231 | 0.86 | MEN1 (0.47) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL11116675 | 0.85 | TLR7 (0.34) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10381556 | 0.80 | MEN1 (0.50) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10377601 | 0.79 | MEN1 (0.52) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10734712 | 0.78 | MEN1 (0.51) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10378779 | 0.78 | MEN1 (0.51) | MEN1KMT2ATTRPPOXTDP1 | |
| Ammonia Solution, Strong SCHEMBL10379183 | 0.78 | MEN1 (0.51) | MEN1KMT2ATTRPPOXTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |