Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127651 | 0.94 | CYP3A4 (0.36) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9137901 | 0.85 | MEN1 (0.48) | ALDH1A1MEN1KMT2ATTRPPOX | |
| SCHEMBL10796463 | 0.80 | RAB9A (0.38) | TLR7CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11126540 | 0.79 | KMT2A (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10830718 | 0.77 | ALDH1A1 (0.38) | TLR7ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10750510 | 0.77 | MAOB (0.50) | TLR7CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10669968 | 0.76 | KMO (0.52) | TLR7CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10803315 | 0.76 | TLR7 (0.42) | TLR7CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10810845 | 0.75 | MRGPRX4 (0.48) | TLR7CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8700324 | 0.75 | TDP1 (0.40) | ALDH1A1CYP3A4MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124985-A1 | Herbicidal diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | disclosed |