Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 12/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143335 | 0.94 | P4HTM (0.58) | P4HTMSMN1; SMN2LMNAMAPK1NPC1 | |
| SCHEMBL8869631 | 0.94 | P4HTM (0.53) | P4HTMEGFRCA2SMN1; SMN2LMNA | |
| SCHEMBL9139700 | 0.91 | P4HTM (0.53) | P4HTMEGFRCA2SMN1; SMN2LMNA | |
| SCHEMBL8868196 | 0.91 | P4HTM (0.53) | P4HTMEGFRCA2SMN1; SMN2NPC1 | |
| SCHEMBL8868013 | 0.91 | P4HTM (0.50) | P4HTMEGFRCA2SMN1; SMN2LMNA | |
| SCHEMBL8869667 | 0.91 | P4HTM (0.53) | P4HTMEGFRCA2SMN1; SMN2NPC1 | |
| SCHEMBL9136898 | 0.90 | P4HTM (0.65) | P4HTMEGFRSMN1; SMN2MAPK1NPC1 | |
| SCHEMBL8868438 | 0.90 | P4HTM (0.48) | P4HTMEGFRCA2SMN1; SMN2LMNA | |
| SCHEMBL8867931 | 0.90 | HPGD (0.51) | P4HTMEGFRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9139791 | 0.90 | P4HTM (0.49) | P4HTMEGFRCA2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |