Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138808 | 0.91 | LPAR1 (0.41) | LPAR1 | |
| SCHEMBL9139774 | 0.90 | LPAR1 (0.40) | LPAR1KCNK3KCNK9 | |
| SCHEMBL7103639 | 0.84 | — | — | |
| SCHEMBL9138047 | 0.81 | LPAR1 (0.40) | LPAR1TAS2R14 | |
| SCHEMBL9136927 | 0.80 | — | — | |
| SCHEMBL9136104 | 0.80 | CA12 (0.39) | — | |
| SCHEMBL9137804 | 0.77 | — | — | |
| SCHEMBL9359108 | 0.77 | — | — | |
| SCHEMBL9137934 | 0.77 | CA12 (0.42) | — | |
| SCHEMBL9707997 | 0.75 | TAS2R14 (0.36) | TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384328-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0555351-B1 | OXYSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5245068-A | Acylcoenzyme A cholesterol acyltransferase inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1992007826-A1 | OXYSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |