Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.44 |
| ▸ | PGR | P06401 | 7/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.38 |
| ▸ | SHBG | P04278 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138417 | 1.00 | AR (0.44) | ARPGRNR3C2MAPTCYP2C19 | |
| SCHEMBL9140431 | 0.88 | AR (0.53) | ARPGRNR3C2MAPTCYP2C19 | |
| SCHEMBL9140435 | 0.88 | AR (0.53) | ARPGRNR3C2MAPTCYP2C19 | |
| SCHEMBL9136995 | 0.81 | SERPINA6 (0.52) | ARPGRMAPTCYP2C19CYP3A4 | |
| SCHEMBL9136998 | 0.81 | SERPINA6 (0.52) | ARPGRMAPTCYP2C19CYP3A4 | |
| SCHEMBL9141520 | 0.75 | AR (0.34) | ARPGRNR3C2MAPTCYP2C19 | |
| SCHEMBL9141523 | 0.75 | AR (0.34) | ARPGRNR3C2MAPTCYP2C19 | |
| SCHEMBL10805580 | 0.74 | AR (0.52) | ARPGRMAPTCYP2C19CYP3A4 | |
| SCHEMBL9138297 | 0.73 | AR (0.47) | ARPGRNR3C2MAPTCYP2C19 | |
| SCHEMBL9138301 | 0.73 | AR (0.47) | ARPGRNR3C2MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478862-A | Having progestational activity with minimum ancillary hormonal activity; antiovulation agents | SRI INTERNATIONAL (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0500899-B1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | STANFORD RES INST INT (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5321044-A | Ovulation suppression | SRI INTERNATIONAL (US) | 1994-06-14 | — | — | US | disclosed |
| US-5116865-A | Antifertility Agents | SRI INTERNATIONAL, A CORP OF CA | 1992-05-26 | — | — | US | disclosed |
| WO-1992004309-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | SRI INTERNATIONAL (US) | 1992-03-19 | — | — | WO | disclosed |