SCHEMBL9138481

SCHEMBL9138481

c1c(C2CCCCC2)nnn1CN1CCN(Cn2cc(C3CCCCC3)nn2)CC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.57
HRH4 Q9H3N8 3/20 0.48
HRH3 Q9Y5N1 3/20 0.48
DPP4 P27487 1/20 0.44
MIF P14174 1/20 0.44
KMT2A Q03164 1/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
JAK2 O60674 1/20 0.37
ROCK2 O75116 1/20 0.37
GSK3B P49841 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
GPR88 Q9GZN0 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21016237 0.79 CYP19A1 (0.60) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL19535293 0.77 CYP19A1 (0.58) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL9091212 0.77 CYP19A1 (0.57) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL23978355 0.75 CYP19A1 (0.56) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL19535202 0.75 CYP19A1 (0.55) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL26947314 0.74 CYP19A1 (0.55) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL25217051 0.74 CYP19A1 (0.58) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL22321067 0.73 CYP19A1 (1.00) CYP19A1HRH4HRH3MIFNPC1
SCHEMBL19535084 0.72 HRH4 (0.56) CYP19A1HRH4HRH3DPP4MIF
SCHEMBL21286188 0.71 DPP4 (0.54) CYP19A1HRH4HRH3DPP4MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5441563-A Antifoam agents in printing inks ARMSTRONG WORLD INDUSTRIES, INC. (US) 1995-08-15 US claimed
US-5441563-A Antifoam agents in printing inks ARMSTRONG WORLD INDUSTRIES, INC. (US) 1995-08-15 US disclosed