Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137866 | 0.96 | P4HTM (0.44) | SMN1; SMN2P4HTMKMT2AFBP1BCL2L1 | |
| SCHEMBL9141501 | 0.95 | P4HTM (0.44) | SMN1; SMN2P4HTMKMT2ABCL2L1MCL1 | |
| SCHEMBL9139408 | 0.93 | KMT2A (0.43) | SMN1; SMN2P4HTMKMT2AFBP1ALDH1A1 | |
| SCHEMBL9139739 | 0.93 | P4HTM (0.46) | P4HTMKMT2ABCL2L1MCL1ALDH1A1 | |
| SCHEMBL9141271 | 0.92 | SMN1; SMN2 (0.49) | SMN1; SMN2P4HTMKMT2AFBP1BCL2L1 | |
| SCHEMBL9139355 | 0.92 | P4HTM (0.48) | SMN1; SMN2P4HTMKMT2ABCL2L1MCL1 | |
| SCHEMBL9140572 | 0.92 | P4HTM (0.46) | SMN1; SMN2P4HTMKMT2AALDH1A1MAPT | |
| SCHEMBL9140303 | 0.91 | P4HTM (0.44) | P4HTMKMT2AFBP1BCL2L1MCL1 | |
| SCHEMBL9139623 | 0.91 | P4HTM (0.46) | SMN1; SMN2P4HTMKMT2AALDH1A1MAPT | |
| SCHEMBL9142109 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2P4HTMKMT2AFBP1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |