Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137873 | 0.96 | P4HTM (0.45) | SMN1; SMN2P4HTMFBP1EGLN1KMT2A | |
| SCHEMBL9141271 | 0.93 | SMN1; SMN2 (0.49) | SMN1; SMN2P4HTMFBP1KMT2ABCL2L1 | |
| SCHEMBL9139411 | 0.91 | RAB9A (0.45) | SMN1; SMN2P4HTMFBP1KMT2AMEN1 | |
| SCHEMBL9139358 | 0.91 | P4HTM (0.50) | SMN1; SMN2P4HTMBCL2L1MCL1CASP3 | |
| SCHEMBL9138985 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2P4HTMFBP1KMT2ABCL2L1 | |
| SCHEMBL9139745 | 0.90 | P4HTM (0.47) | P4HTMKMT2AMEN1HPGDCASP3 | |
| SCHEMBL9139559 | 0.89 | P4HTM (0.50) | P4HTMEGLN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL9140576 | 0.89 | P4HTM (0.48) | SMN1; SMN2P4HTMHPGDPAX8 | |
| SCHEMBL9140306 | 0.89 | P4HTM (0.45) | P4HTMFBP1KMT2ABCL2L1MCL1 | |
| SCHEMBL9140170 | 0.89 | P4HTM (0.47) | SMN1; SMN2P4HTMFBP1KMT2ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |