Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.60 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141149 | 0.97 | OPRM1 (0.60) | OPRM1OPRL1PSEN1PSEN2APH1B | |
| SCHEMBL10084139 | 0.87 | SLC6A4 (0.54) | OPRM1OPRL1ALDH1A1SLC6A4SLC6A2 | |
| SCHEMBL14278986 | 0.86 | CCR1 (0.52) | OPRM1OPRL1ALDH1A1TP53GAA | |
| SCHEMBL9138637 | 0.84 | TBXA2R (0.59) | OPRM1OPRL1GAASLC6A4SLC6A2 | |
| SCHEMBL14278985 | 0.84 | SLC6A4 (0.54) | OPRM1OPRL1ALDH1A1TP53GAA | |
| SCHEMBL9143710 | 0.82 | CA1 (0.48) | OPRM1OPRL1ALDH1A1TP53GAA | |
| SCHEMBL9138716 | 0.81 | TBXA2R (0.59) | OPRM1OPRL1GAASLC6A4SLC6A2 | |
| SCHEMBL26920900 | 0.81 | CCR1 (0.56) | OPRM1OPRL1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9143964 | 0.80 | TBXA2R (0.58) | OPRM1OPRL1GAASLC6A4SLC6A2 | |
| SCHEMBL9143385 | 0.80 | SLC6A2 (0.49) | OPRM1OPRL1ALDH1A1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476846-A | Administering anti-thrombotic and anti-asthmatic agent | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1995-12-19 | — | — | US | disclosed |
| US-5387709-A | Bronchodilator agents, anticoagulants, vasodilation | LIPHA LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0472449-B1 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0472449-A2 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-02-26 | — | — | EP | disclosed |