Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139088 | 0.91 | P4HTM (0.72) | P4HTMLMNAPTPN1GABRA5MAPT | |
| SCHEMBL9142963 | 0.89 | P4HTM (0.55) | P4HTMLMNAPTPN1GABRA5MAPT | |
| SCHEMBL9140452 | 0.88 | P4HTM (0.53) | P4HTMLMNAPTPN1GABRA5MAPT | |
| SCHEMBL9018572 | 0.88 | P4HTM (0.77) | P4HTMPTPN1ALDH1A1NPC1RAB9A | |
| SCHEMBL9143052 | 0.87 | P4HTM (0.52) | P4HTMLMNAPTPN1GABRA5MAPT | |
| SCHEMBL9140278 | 0.87 | P4HTM (0.52) | P4HTMLMNAPTPN1GABRA5MAPT | |
| SCHEMBL8869393 | 0.87 | P4HTM (0.63) | P4HTMPTPN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9139661 | 0.84 | P4HTM (0.72) | P4HTMLMNAPTPN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9137797 | 0.84 | P4HTM (0.66) | P4HTMLMNA | |
| SCHEMBL9140658 | 0.83 | GABRA5 (0.49) | P4HTMPTPN1GABRA5MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |