Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803712 | 0.84 | PLD1 (0.33) | TRPA1GAAMCHR1KMT2AKDM1A | |
| SCHEMBL9139320 | 0.83 | SLC18A2 (0.33) | TRPA1MCHR1 | |
| SCHEMBL8806120 | 0.82 | CYP2D6 (0.36) | TRPA1MAPTCYP2D6CYP2C19KMT2A | |
| SCHEMBL8804858 | 0.81 | CYP2D6 (0.36) | MAPTCYP2D6CYP2C19MCHR1KMT2A | |
| SCHEMBL8804147 | 0.81 | SLC18A2 (0.33) | MCHR1KDM1AHDAC6HSD17B2 | |
| SCHEMBL8804868 | 0.80 | CYP2D6 (0.35) | MAPTCYP2D6CYP2C19KMT2ARXFP1 | |
| SCHEMBL9142589 | 0.80 | CYP2D6 (0.35) | TRPA1MAPTCYP2D6CYP2C19KMT2A | |
| SCHEMBL8804087 | 0.79 | TSHR (0.35) | MAPTCYP2D6CYP2C19KMT2ARXFP1 | |
| SCHEMBL8803350 | 0.78 | IDO1 (0.34) | MCHR1KMT2AKDM1A | |
| SCHEMBL8878777 | 0.77 | MAPT (0.35) | MAPTCYP2D6CYP2C19KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |