Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139320 | 0.89 | SLC18A2 (0.33) | SLC18A2HTR2ASLC6A3PLD1MCHR1 | |
| SCHEMBL9143590 | 0.86 | GFER (0.33) | PLD1TACR1 | |
| SCHEMBL8803712 | 0.84 | PLD1 (0.33) | SLC18A2HTR2ASLC6A3PLD1MCHR1 | |
| SCHEMBL8806120 | 0.81 | CYP2D6 (0.36) | HTR2ASLC6A3ALDH1A1 | |
| SCHEMBL9139737 | 0.81 | TRPA1 (0.34) | MCHR1KDM1AHDAC6HSD17B2 | |
| SCHEMBL8804650 | 0.78 | NPSR1 (0.37) | HTR2ASLC6A3ALDH1A1 | |
| SCHEMBL8803350 | 0.78 | IDO1 (0.34) | SLC18A2HTR2ASLC6A3PLD1MCHR1 | |
| SCHEMBL8804858 | 0.77 | CYP2D6 (0.36) | HTR2ASLC6A3MCHR1ALDH1A1 | |
| SCHEMBL9142589 | 0.76 | CYP2D6 (0.35) | HTR2ASLC6A3ALDH1A1 | |
| SCHEMBL8804868 | 0.76 | CYP2D6 (0.35) | HTR2ASLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647231-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS, ETC. | BASF AG (DE) | 1997-08-27 | — | — | EP | disclosed |