Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625017 | 0.83 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL8434329 | 0.79 | AGTR1 (0.55) | AGTR1 | |
| SCHEMBL8434213 | 0.78 | AGTR1 (0.56) | AGTR1 | |
| SCHEMBL7622990 | 0.76 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL7630059 | 0.76 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL7628768 | 0.75 | — | — | |
| SCHEMBL9139807 | 0.75 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL6972578 | 0.75 | — | — | |
| SCHEMBL7621589 | 0.74 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL7628739 | 0.74 | AGTR1 (0.64) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451597-A | Hypotensive agents, congestive heart failure | G.D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | claimed |