D-Alanine

D-Alanine

SCHEMBL9140010

C[C@@H](N)C(=O)O.C[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)O.C[C@H](N)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.61
NOD1 Q9Y239 1/20 0.47
ITGB2 P05107 2/20 0.43
ICAM1 P05362 2/20 0.43
ITGAL P20701 2/20 0.43
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
ACE P12821 1/20 0.42
DPP4 P27487 1/20 0.41
CA2 P00918 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
CA1 P00915 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MME P08473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473104 0.98 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL11517272 0.98 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL5582285 0.98 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL30910815 0.98 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL2490629 0.98 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL31390152 0.95 ECE1 (0.59) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL20789058 0.91 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL20263697 0.91 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL31026346 0.91 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL31026345 0.91 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5429949-A S-triazine degrading bacteria OHIO STATE RESEARCH FOUNDATION (US) 1995-07-04 US disclosed