SCHEMBL2490629

SCHEMBL2490629

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nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.63
NOD1 Q9Y239 1/20 0.48
ITGB2 P05107 2/20 0.44
ICAM1 P05362 2/20 0.44
ITGAL P20701 2/20 0.44
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
ACE P12821 1/20 0.43
DPP4 P27487 1/20 0.42
CA2 P00918 2/20 0.42
ALDH1A1 P00352 1/20 0.42
RAB9A P51151 1/20 0.42
CA1 P00915 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MME P08473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473104 1.00 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL30910815 1.00 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL11517272 1.00 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL5582285 1.00 ECE1 (0.63) ECE1NOD1ITGB2ICAM1ITGAL
D-Alanine SCHEMBL9140010 0.98 ECE1 (0.61) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL31390152 0.96 ECE1 (0.59) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL20789058 0.93 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL31026346 0.93 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL20263697 0.93 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL
SCHEMBL31026345 0.93 ECE1 (0.56) ECE1NOD1ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748843-A2 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2026-05-27 EP claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 WO claimed
CN-122031713-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 乐普生物科技股份有限公司 2026-05-15 CN claimed
CN-122028936-A Antibody-drug conjugates ADC疗法责任有限公司 2026-05-12 CN claimed
EP-4735021-A1 COMBINATION THERAPY Zealand Pharma A/S (DK) 2026-05-06 EP claimed
EP-4731239-A1 ANALOGUES WITH IMPROVED PROPERTIES Zealand Pharma A/S (DK) 2026-04-29 EP claimed
EP-4074729-B1 AMYLIN ANALOGUES ZEALAND PHARMA AS (DK) 2026-04-15 EP claimed
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2026-03-26 US claimed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 EP claimed
WO-2026044039-A2 ANTI-CD73 ANTIBODIES, CONJUGATES, AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-02-26 WO claimed
CN-114805489-A Polypeptide for repairing skin injury or mucous membrane injury and application thereof 四川好医生攀西药业有限责任公司 2022-07-29 CN claimed
WO-2022150637-A1 NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF IMMUNEXT, INC. (US) 2022-07-14 WO claimed
WO-2022148289-A1 POLYPEPTIDE FOR REPAIRING SKIN WOUND OR MUCOSAL INJURY, AND APPLICATION THEREOF 四川好医生攀西药业有限责任公司 2022-07-14 WO claimed
US-11382956-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2022-07-12 US claimed
CN-114450293-A Anthracycline derivatives 阿尔麦克探索有限公司 2022-05-06 CN claimed
US-20220105050-A1 PROPOFOL PRODRUG METHODS AND COMPOSITIONS EPALEX CORPORATION 2022-04-07 US claimed
WO-2022058395-A1 ANTIBODY-EXATECAN CONJUGATES SYNAFFIX B.V. (NL) 2022-03-24 WO claimed
EP-0357784-B1 A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-09-02 EP claimed
EP-0357784-A1 A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES. KYOWA HAKKO KOGYO KK (JP) 1990-03-14 EP claimed
WO-1989006497-A1 A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-07-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF KLK3, FOLH1, PSMA1 ECE1 2478/4885NOD1 2061/4885ITGB2 362/4885
US-11382956-B2 Amylin analogues IAPP, GLP1R, AMY2A ECE1 584/4885NOD1 666/4885ITGB2 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.