Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140080 | 1.00 | PARP1 (0.46) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL9140087 | 1.00 | PARP1 (0.46) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL9142006 | 1.00 | PARP1 (0.46) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL9141998 | 1.00 | PARP1 (0.46) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL9142139 | 0.79 | GPR119 (0.47) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL9142136 | 0.79 | GPR119 (0.47) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL9142142 | 0.79 | GPR119 (0.47) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL21738004 | 0.77 | PARP1 (0.44) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL21737995 | 0.77 | PARP1 (0.44) | PARP1GPR119HSD11B1HDAC1CCR2 | |
| SCHEMBL1199139 | 0.76 | GPR119 (0.47) | PARP1GPR119HSD11B1HDAC1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478939-A | Muscarinic agents | AMERICAN CYANAMID COMPANY (US) | 1995-12-26 | — | — | US | claimed |
| US-5478939-A | Muscarinic agents | AMERICAN CYANAMID COMPANY (US) | 1995-12-26 | — | — | US | disclosed |