Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140291 | 1.00 | PTGS1 (0.40) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL9138676 | 0.97 | PTGS1 (0.43) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL9138675 | 0.97 | PTGS1 (0.43) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL8230399 | 0.84 | KDM4E (0.44) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL11640859 | 0.84 | KDM4E (0.44) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| Lysine SCHEMBL11543542 | 0.83 | GSR (0.41) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| Lysine SCHEMBL11543534 | 0.83 | GSR (0.41) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL11792482 | 0.83 | KDM4E (0.43) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL11792486 | 0.83 | KDM4E (0.43) | PTGS1PTGS2KMT2AHTTOPRK1 | |
| SCHEMBL9141017 | 0.81 | CYP4Z1 (0.42) | PTGS1PTGS2KMT2AHTTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161538-A | 4-(2-OXO- OR HYDROXIMINO-CYCLOALKAN-1-YLMETHYL)-PHENYLACETIC ACID, ANTIINFLAMMATORY AGENTS | SANKYO COMPANY LIMITED (JP) | 1979-07-17 | — | — | US | claimed |
| US-5476846-A | Administering anti-thrombotic and anti-asthmatic agent | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1995-12-19 | — | — | US | disclosed |
| US-5387709-A | Bronchodilator agents, anticoagulants, vasodilation | LIPHA LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0472449-B1 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0472449-A2 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-02-26 | — | — | EP | disclosed |
| US-4161538-A | 4-(2-OXO- OR HYDROXIMINO-CYCLOALKAN-1-YLMETHYL)-PHENYLACETIC ACID, ANTIINFLAMMATORY AGENTS | SANKYO COMPANY LIMITED (JP) | 1979-07-17 | — | — | US | disclosed |