Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 9/20 | 0.45 |
| ▸ | RARB | P10826 | 8/20 | 0.45 |
| ▸ | RARA | P10276 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140302 | 1.00 | RARG (0.45) | RARGRARBRARAMAPTHPGD | |
| SCHEMBL26471776 | 0.87 | RARG (0.43) | RARGRARBRARAMAPTHPGD | |
| SCHEMBL9145537 | 0.86 | RARG (0.48) | RARGRARBRARAHPGDHTT | |
| SCHEMBL9145541 | 0.86 | RARG (0.48) | RARGRARBRARAHPGDHTT | |
| SCHEMBL8460903 | 0.86 | DRD3 (0.44) | RARGRARBRARAMAPTHPGD | |
| SCHEMBL8460900 | 0.86 | DRD3 (0.44) | RARGRARBRARAMAPTHPGD | |
| SCHEMBL8457141 | 0.85 | RARG (0.54) | RARGRARBRARARAB9ANPC1 | |
| SCHEMBL8457147 | 0.85 | RARG (0.54) | RARGRARBRARARAB9ANPC1 | |
| SCHEMBL9144382 | 0.83 | RARB (0.51) | RARGRARBRARAMAPTHPGD | |
| SCHEMBL9144389 | 0.83 | RARB (0.51) | RARGRARBRARAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420273-A | Skin disorders and antitumor agents | HOFFMAN-LA ROCHE INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5164387-A | Antitumor agents, skin disorders, antiinflammatory agents | HOFFMANN-LAROCHE INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5037825-A | Useful In The Treatment Of Neoplasms, Dermatoses And Aging Of The Skin | HOFFMANN-LA ROCHE INC. (US) | 1991-08-06 | — | — | US | disclosed |