Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869195 | 0.93 | MAPT (0.50) | P4HTMAKR1C3MAPTPPARARAB9A | |
| SCHEMBL9138339 | 0.92 | P4HTM (0.65) | P4HTMAKR1C3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9143635 | 0.92 | P4HTM (0.58) | P4HTMAKR1C3PPARARAB9ANPC1 | |
| SCHEMBL9137965 | 0.91 | P4HTM (0.57) | P4HTMAKR1C3MAPTRAB9ANPC1 | |
| SCHEMBL9140238 | 0.90 | PPARA (0.49) | P4HTMAKR1C3MAPTPPARARAB9A | |
| SCHEMBL9139923 | 0.89 | P4HTM (0.60) | P4HTMMAPTPPARARAB9ANPC1 | |
| SCHEMBL9141303 | 0.89 | P4HTM (0.60) | P4HTMMAPTPPARARAB9ANPC1 | |
| SCHEMBL8867979 | 0.89 | PPARA (0.49) | P4HTMAKR1C3MAPTPPARARAB9A | |
| SCHEMBL9139090 | 0.89 | PPARA (0.48) | P4HTMAKR1C3MAPTPPARARAB9A | |
| SCHEMBL9140053 | 0.88 | AKR1C3 (0.57) | P4HTMAKR1C3MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |