Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868537 | 0.92 | RAB9A (0.45) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9140238 | 0.92 | PPARA (0.49) | PPARAAKR1C3MAPTMEN1KMT2A | |
| SCHEMBL8868797 | 0.92 | SMN1; SMN2 (0.49) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL8869533 | 0.92 | PPARA (0.49) | PPARAAKR1C3MAPTMEN1KMT2A | |
| SCHEMBL8869195 | 0.91 | MAPT (0.50) | PPARAAKR1C3MAPTNPC1RAB9A | |
| SCHEMBL8869085 | 0.91 | P4HTM (0.52) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8869577 | 0.90 | EGFR (0.53) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL8869604 | 0.90 | EGFR (0.53) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7874565 | 0.90 | PPARA (0.46) | PPARAAKR1C3MAPTMEN1KMT2A | |
| SCHEMBL9140459 | 0.89 | P4HTM (0.57) | PPARAAKR1C3MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |