Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141279 | 1.00 | RCE1 (0.49) | RCE1HTTMAPTIDO1SLC1A3 | |
| SCHEMBL9141079 | 0.79 | MAPT (0.54) | RCE1HTTMAPTSLC1A3SLC1A2 | |
| SCHEMBL9141085 | 0.79 | MAPT (0.54) | RCE1HTTMAPTSLC1A3SLC1A2 | |
| SCHEMBL2644673 | 0.77 | TSHR (0.48) | RCE1IDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8766555 | 0.77 | TSHR (0.68) | HTTMAPTIDO1CYP1A2CYP2C19 | |
| SCHEMBL3919240 | 0.76 | SLC1A3 (0.47) | RCE1MAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL14393103 | 0.76 | SMN1; SMN2 (0.43) | RCE1HTTMAPTIDO1SLC1A3 | |
| SCHEMBL7763413 | 0.75 | RCE1 (0.46) | RCE1HTTIDO1SLC1A3SLC1A2 | |
| SCHEMBL7763405 | 0.75 | RCE1 (0.46) | RCE1HTTIDO1SLC1A3SLC1A2 | |
| SCHEMBL28631415 | 0.75 | RCE1 (0.43) | RCE1HTTMAPTIDO1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432273-A | Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol | EMORY UNIVERSITY (US) | 1995-07-11 | — | — | US | disclosed |
| US-5414078-A | Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors | EMORY UNIVERSITY (US) | 1995-05-09 | — | — | US | disclosed |