SCHEMBL91418

SCHEMBL91418

Cc1ccc(Cl)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30167594 1.00
SCHEMBL11980732 0.84 AKR1C3 (0.51)
SCHEMBL13471707 0.81 ALOX5 (0.43)
SCHEMBL935657 0.81
SCHEMBL16574104 0.81 MAP4K4 (0.48)
SCHEMBL6650982 0.79 CYP3A4 (0.46)
SCHEMBL29443091 0.77
SCHEMBL530450 0.77
SCHEMBL12999936 0.77 ESR2 (0.58)
SCHEMBL22508626 0.75 SLC6A4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 958 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-112851501-A Chemical tracer for fracturing and preparation method and application thereof 中国石油大学(华东) 2021-05-28 CN claimed
CN-106748725-B preparation method of 4-chloro-2-fluoro-phenylpropionic acid 贵州大学 2020-01-31 CN claimed
CN-110590673-A 4-chloro-7-methyl-1H-indazole and chemical synthesis method thereof 南通大学 2019-12-20 CN claimed
CN-102786386-B Preparation method of 4-chloro-2-fluorotoluene SHANDONG FUER CO LTD 2015-01-21 CN claimed
CN-102786386-A Preparation method of 4-chloro-2-fluorotoluene SHANDONG FUER CO LTD 2012-11-21 CN claimed
WO-2012090179-A2 ISOQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS LUPIN LIMITED (IN) 2012-07-05 WO claimed
EP-1539753-B1 PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LTD (GB) 2009-09-09 EP claimed
US-20080175914-A1 Pyrazolo[3,4-b]Pyridine Compounds, and their Use as Phosphodiesterase Inhibitors GLAXO GROUP LIMITED 2008-07-24 US claimed
US-20070065360-A1 Nonpolar thymidine analogs NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-03-22 US claimed
US-20060089375-A1 Pyrazolo[3,4-b] pyridine compounds, and their use as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2006-04-27 US claimed
EP-1539753-A2 PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2005-06-15 EP claimed
WO-2004024728-A2 PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-03-25 WO claimed
EP-0653412-B1 Process for preparing 4,5-difluorobenzaldehydes BAYER AG (DE) 1998-01-21 EP claimed
US-5489715-A Process for preparing 4,5-difluorobenzaldehydes BAYER AKTIENGESELLSCHAFT (DE) 1996-02-06 US claimed
EP-3227270-B1 HETEROCYCLIC DERIVATIVES AND USE THEREOF C&C RES LAB (KR) 2024-11-13 EP disclosed
EP-4400172-A2 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS Incyte Holdings Corporation (US) 2024-07-17 EP disclosed
US-4046905-A Anti-inflammatory, analgesic and antipyretic phenylacetic acids MERCK & CO., INC. (US) 1977-09-06 US disclosed
US-3985799-A 2-Fluoro-6-trifluoromethylbenzoic acid SANDOZ, INC. (US) 1976-10-12 US disclosed
US-3947582-A Phenylacetic acid compounds in treating abnormal platelet aggregation MERCK & CO., INC. (US) 1976-03-30 US disclosed