Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL9141900

CCC(C)(C)O.OCCOCCO

nearest known ligand 0.56

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
MAPK1 P28482 2/20 0.56
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 3/20 0.52
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
CASP1 P29466 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLCO1B3 Q9NPD5 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amylene Hydrate SCHEMBL10534216 0.89 MEN1 (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Butoxyethanol SCHEMBL8467584 0.89 TSHR (0.74) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL29117919 0.86 TSHR (0.59) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL3510739 0.81 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL16685273 0.81 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14606164 0.79 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL2805801 0.79 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL5456660 0.79 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL2803264 0.79 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL16685288 0.79 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5437952-A Lithographic photosensitive printing plate comprising a photoconductor and a naphtho-quinone diazide sulfonic acid ester of a phenol resin KONICA CORPORATION (JP) 1995-08-01 US disclosed
US-5380612-A Forming electrophotographic latent image on photoconductive layer of photosensitive planographic plate, developing to form toner image, uniformly exposing photoconductor to actinic light, removing photoconductive layer with no toner image KONICA CORPORATION (JP) 1995-01-10 US disclosed