Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142156 | 1.00 | KMT2A (0.45) | KMT2APKMMEN1NPC1HSP90AA1 | |
| SCHEMBL4971386 | 0.86 | AKR1B1 (0.44) | KMT2AMEN1NPSR1MAPTALDH1A1 | |
| SCHEMBL4971376 | 0.86 | AKR1B1 (0.44) | KMT2AMEN1NPSR1MAPTALDH1A1 | |
| SCHEMBL9845496 | 0.83 | AKR1B1 (0.40) | KMT2AMEN1MAPTALDH1A1AKR1B1 | |
| SCHEMBL9845497 | 0.83 | AKR1B1 (0.40) | KMT2AMEN1MAPTALDH1A1AKR1B1 | |
| SCHEMBL16101298 | 0.82 | AKR1B1 (0.46) | KMT2AMEN1MAPTAKR1B1 | |
| SCHEMBL9148051 | 0.79 | AKR1B1 (0.46) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL450748 | 0.79 | AKR1B1 (0.46) | KMT2AMEN1HPGDMAPTALDH1A1 | |
| SCHEMBL27313536 | 0.78 | SMN1; SMN2 (0.44) | KMT2AHPGDMAPTALDH1A1AKR1B1 | |
| SCHEMBL9142319 | 0.78 | AKR1B1 (0.45) | KMT2ANPC1HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420126-A | Potassium channel activators | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0432893-A2 | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |